Paulo Roberto B Evora Selected Research

Vasoplegia

10/2022	Indigo Carmine Hemodynamic Studies to Treat Vasoplegia Induced by Compound 48/80 in a Swine Model of Anaphylaxis.
1/2021	After Thirty Years, We Still Cannot Understand Why Methylene Blue is not a Reference to Treat Vasoplegic Syndrome in Cardiac Surgery.
5/2012	Guanylate cyclase inhibition by methylene blue as an option in the treatment of vasoplegia after a severe burn. A medical hypothesis.
10/2009	Endothelium dysfunction classification: why is it still an open discussion?
12/2006	Is methylene blue of benefit in treating adult patients who develop catecholamine-resistant vasoplegic syndrome during cardiac surgery?
3/2004	Methylene blue as drug of choice for catecholamine-refractory vasoplegia after cardiopulmonary bypass.

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Paulo Roberto B Evora Research Topics

Disease

6	Vasoplegia 10/2022 - 03/2004
6	Anaphylaxis (Anaphylactic Shock) 10/2022 - 09/2002
3	Wounds and Injuries (Trauma) 09/2021 - 07/2015
2	Burns 09/2021 - 05/2012
2	Shock 01/2021 - 09/2002
2	Hemorrhage 07/2015 - 06/2007
2	Inflammation (Inflammations) 05/2014 - 12/2013
2	Hypotension (Low Blood Pressure) 04/2013 - 09/2002
2	Ischemia 09/2007 - 01/2005
1	Necrosis 09/2021
1	COVID-19 01/2020
1	False Aneurysm (Pseudoaneurysm) 01/2020
1	Neoplasms (Cancer) 01/2018
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Seizures (Absence Seizure) 01/2018
1	Melanoma (Melanoma, Malignant) 05/2015
1	Peripheral Arterial Disease 05/2014
1	Hyperplasia 05/2014
1	Fibrosis (Cirrhosis) 01/2014
1	Hypertension (High Blood Pressure) 12/2013
1	Pulmonary Hypertension 12/2013
1	Myocardial Infarction 01/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2011
1	Thrombosis (Thrombus) 10/2009
1	Spasm (Spasms) 10/2009
1	Endocarditis 06/2007
1	Starvation 07/2006
1	Reperfusion Injury 01/2005
1	Hypersensitivity (Allergy) 12/2004
1	Inguinal Hernia (Direct Inguinal Hernia) 12/2004

Drug/Important Bio-Agent (IBA)

12	Methylene Blue (Methylthioninium Chloride)FDA Link 09/2021 - 09/2002
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2021 - 01/2005
3	CatecholaminesIBA 05/2012 - 03/2004
3	Pharmaceutical PreparationsIBA 03/2008 - 03/2004
2	p-Methoxy-N-methylphenethylamineIBA 10/2022 - 03/2008
2	AntioxidantsIBA 09/2021 - 12/2013
2	Protamines (Protamine Sulfate)FDA Link 05/2016 - 09/2002
1	Indigo Carmine (Indigo Blue)IBA 10/2022
1	MetalsIBA 09/2021
1	NitritesIBA 09/2021
1	NitratesIBA 09/2021
1	Malondialdehyde (Propanedial)IBA 09/2021
1	Hemostatics (Antihemorrhagics)IBA 07/2015
1	Matrix Metalloproteinases (MMPs)IBA 05/2014
1	Biomarkers (Surrogate Marker)IBA 12/2013
1	Vitamin E FDA LinkGeneric 12/2013
1	Complement System Proteins (Complement)IBA 01/2013
1	C-Reactive ProteinIBA 01/2013
1	AminesIBA 05/2012
1	Soluble Guanylyl CyclaseIBA 05/2012
1	Guanylate Cyclase (Guanylyl Cyclase)IBA 05/2012
1	Cardiovascular AgentsIBA 07/2011
1	O-methyltyramineIBA 03/2008
1	Formaldehyde (Formol)FDA Link 03/2008
1	Aprotinin (Trasylol)FDA Link 06/2007
1	Saline SolutionIBA 07/2006
1	Sodium Fluoride (Ossin)FDA Link 01/2005
1	Adenosine Diphosphate (ADP)IBA 01/2005
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2005
1	GTP-Binding Proteins (G-Protein)IBA 01/2005
1	Histamine (Histamine Dihydrochloride)FDA Link 12/2004
1	Anesthetics (Anesthetic Agents)IBA 12/2004

Therapy/Procedure

2	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2018 - 03/2004
2	Resuscitation 07/2015 - 05/2012
1	Intradermal Injections 09/2021
1	Sutures (Suture) 01/2020
1	Drug Therapy (Chemotherapy) 01/2018
1	Metastasectomy 05/2015
1	Stents 05/2014
1	Liver Transplantation 01/2014
1	Prostheses and Implants (Prosthesis) 06/2007
1	Anesthesia 12/2004
1	Therapeutics 12/2004
1	Spinal Anesthesia 12/2004